TRANSFUSION MEDICINE

The RAD-CONTROL blood irradiation indicator serves to verify the irradiation of blood products. The intended use is for gamma or X-Ray blood irradiation with at least 25 gray. A RAD-CONTROL label is affixed to the blood product before blood irradiating takes place. The indicator will turn from RED to BLACK once irradiation has been carried out.
This change in color is reliable and self-explanatory! There are no evaluation uncertainties, only clear information of ‘not irradiated/irradiated’. RAD-CONTROL blood irradiation indicators are carefully produced and comprehensively tested in accordance with our ISO 13485 quality management system to avoid any risk in your processes.

After blood irradiation the RAD-CONTROL BARCODE irradiation indicator appears as a barcode. This globally unique indicator enables:
Electronic readability of the blood irradiation result.
Automation of the blood irradiation process.
Improvement and simplification of the entire process.
Additionally the word "IRRADIATED" appears in a second field to also show to users clearly that the irradiation was performed. The marking of labels or the manual entry of blood irradiation results is no longer necessary. After setting up the system blood bags can be distributed only if they have been identified and verification of blood irradiation has been confirmed..
This change in color is reliable and self-explanatory! There are no evaluation uncertainties, only clear information of ‘not irradiated/irradiated’. RAD-CONTROL BARCODE blood irradiation indicators are carefully produced and comprehensively tested in accordance with our ISO 13458 quality management system to avoid any risk in your processes.

The RAD-CONTROL "SCALE" is a semi-quantitative blood irradiation indicator. The indicator field changes from light PINK to BLUE.
Blood irradiation produces different shades of blue to make it possible to classify irradiation results between a minimum and a maximum value.
RAD-CONTROL "SCALE" is carefully produced and comprehensively tested in accordance with our quality management system to avoid any risk in your processes.

LIFECODES MACE1 provides a well-characterized monoclonal antibody immobilized in the microdiodes used to capture glycoproteins from platelets provided by the user. This product allows the user to detect and differentiate antibodies that bind to specific platelet glycoproteins. The MACE kit offers tests that can be used either to identify antibodies (if using previously typed platelets) or for platelet compatibility (if to use platelets from a potential donor).
It differentiates anti-platelet and anti-HLA reactions between donor and recipient.
Assistance in interpreting the compatibility results for selecting the appropriate platelet units.
Identifies donor-specific anti-platelet antibodies.

Platelets express polymorphic glycoproteins that may become the target of antibody reactions. The detection of these antibodies provides the clinician the ability to better identify compatible blood products and improve patient care.
The Pak product range offers well-characterized platelet glycoproteins immobilized directly and / or captured by monoclonal antibodies in the wells of a microgrid boards. Available formats allow the user to detect antibodies that bind to HLA-specific platelet glycoproteins.
Class I (IIb / IIIa, Ib / IX, Ia / IIa and IV).
 PakAuto was designed to detect autoantibodies to the patient's glycoproteins. These antibodies are eluted from the patient's platelets or are found in plasma.
Kits available for the detection of platelet and anti-platelet antibodies.
It differentiates HLA from platelet antibodies.
Different sizes of kits for maximum flexibility.

The presence of pre-existing HLA antibodies in blood donors is associated with TRALI (acute transfusion-associated lung injury) and transfusion reactions TRALI type to recipients of blood products from sensitized donors. TRALI is a syndrome described as a spectrum of clinical symptoms that occur very fast (usually within 1-2 hours) after transfusion of blood products. Although it occurs in a small number of patients receiving blood products, remains the leading cause of transfusion-related mortality reported to the Food and Drug Administration.
Screening for HLA antibody screening is now available to the Blood Bank laboratory in a convenient kit called LIFECODES DonorScreen HLA. DonorScreen-HLA was specifically designed to detect these antibodies in blood donors, using the QuickStep tool for automatic processing of ELISA.
QuickStep automation allows the screening of 176 donor samples for HLA antibodies from both Class I and Class II in a single cycle.
Most reagents in the kit are ready for use and can be placed directly on the instrument.
Automation allows use without the presence of personnel.
Donor samples stored up to 96 hours at room temperature in a primary collection tube may be used.
Plasma or serum can be used.
The system accepts eight (8) barcodes at the same time, including: Code 128, Code 39, Pharmacode, Codabar.
The barcode reagent bottles eliminate the preparation mistakes.
Reading the bar code of the sample from the donor ensures the traceability of the data.

Human platelet antibodies (HPAs) may be the target of alloimmune or autoimmune antibody reactions, leading to life-threatening coagulation disorders. danger, such as thrombocyte transfusion rejection reactions, post-transfusion purpura and neonatal allograft thrombocytopenia.
LIFECODES ThromboType and ThromboType1 replace platelet serological testing and, in the case of HLA compatibility, help in platelet selection compatible for recipients with aloimmunity. ThromboType contains the reagents needed to identify a person's genotype for HPA-1, 2, 3, 4, 5, 6 and 15, using gel. ThromboType1 contains the reagents needed to identify a person's genotype for HPA-1 using gel.
Less than 100 minutes from DNA to results.
Pretreated gel without buffer included.
Complex typing of the most common HPA alleles.

Red Blood Cell-Ready Gene is the inno-train product line for the analysis of red blood cell systems based on the SSP-PCR method. Through therefore, these diagnostic systems ideally complement the serological typing of blood groups. The modular concept of the kit gives you freedom to select the systems you want to use. We offer maximum adaptability to your requirements or questions. The evaluation is carried out by standard electrophoresis on agarose gel. As an internal PCR control, each tube contains primers for amplification of the human growth hormone.
If no specific product is present after PCR, the amplification product of this positive control must be clearly detectable.
All Ready Gene kits conform to the EC Directive DDIV 98/79 / EC, have the CE mark and are manufactured according to the quality systems accredited to DIN EN ISO13485: 2012.

Patients with a low ABO or questionable pattern of isoagglutinins can be retiped with the RBC-Ready Gene ABO / ABO Subtype, to the lowest antigens. The flexible format of the RBC-Ready Gene allows the use of both kits in parallel or only for the subtype, depending on your requirements.

To clarify serologically weak D typing in patients and donors, you can use the RBC-Ready Gene CDE and RBC-ReadyGene D weak inno-train systems separately or in combination. The blurred samples are specially tested for categories D, partially D and weak D and, therefore, can be clearly characterized.

With the RBC-Ready Gene CDE system, a clear result of the RHCE C, c, E, e and CW alleles is obtained. in the case of a clear molecular typing for RHCE accompanied by a reaction low C, c, E or e serology, we recommend using the latest RBC-Ready Gene RHCE variants of the test system for clarification. They are too useful for analyzing abnormal serological typing, such as unanticipated RH antibodies. In addition, they can be used for donor / patient testing as well regarding various manifestations of modified RHCE.

Different hemolytic diseases, for example sickle cell anemia (siclemia) or thalassemia, but also the complex evolution of some diseases as a result of multiple operations due to accidents or chronic diseases, it requires permanent blood transfusions. As a result, the blood of the recipients is a difficult mixture blood group screening, especially the Kell, Kidd, Duffy and MNS blood groups. If other transfusions are needed, the molecular detection of the group Blood provides clear results because the amount of donor DNA in the transfused blood units does not influence the test. Also, RBC-Ready Gene confers safety in typing patients who have created allograft or auto-antibodies and / or has positive DAT at serological typing.

Samples from polytransfused patients or patients producing allu / auto-antibodies generally require unambiguous molecular clarification. The new RBC-Ready Gene system vERYfy offers a combined solution for parallel analysis of Rhesus, MNS, Kell, Kidd, Duffy and Dombrock blood groups.

In many cases, antisera for rare blood groups are not available or difficult to obtain. Occasionally, patients develop antibodies difficult to identify which acts against rare blood groups. With Ready Gene Rare ID, alleles of rare blood groups can be detected in a way clear and inexpensive.
In the context of globalization, the demand for blood units with rare alleles is increasing. Our screening concepts for blood group alleles rare will help you find the most appropriate method of keeping blood. You can choose from: RBC-Ready Gene Rare Screen system with 1 the only reaction for 5 different blood group alleles. RBC-Ready Gene 4-Screen tests 4 reactions for 7 different alleles of rare blood groups parallel to the confirmation of D positive or D negative. Further identification of the rare allele detected after such a screening test may be completed with the RBC-Ready Gene Rare ID system.

Six types of DNA, prepped for blood groups and HPA. It is used for molecular biological detection of blood group or HPA. concentration 40ng / µl in 10mM TE. Ready to use.

FluoGene is a unique molecular typing method for HLA-, RBC- and HPA, combining all the advantages of SSP-PCR with the speed of fluorescence signal detection. The analysis is based on a specially modified TaqMan® probe system detected with the FluoVista Analyzer.
All FluoGene kits comply with EC Directive DDIV 98/79 / EC, are CE marked and are manufactured according to accredited quality systems. DIN EN ISO13485: 2012.

BENEFITS

PCR-SSP method without gel electrophoresis in 90 minutes.
No hybridization and washing.
Display of typing results immediately after post-reading.
No risk of post-PCR contamination.
Low DNA consumption.
Software solution easy to use, fully automatic calculation of results.
Same system for HLA-, RBC- and HPA.

EldonCards for blood group determination ABO- and RhD based on the principle of direct agglutination.

Eldoncards are:

Portable, compact and easy to use.
Blood group determination is possible on the spot.
Fast results - in just 2.5 minutes.
Refrigeration, electricity consumption and daily reagent checks are not required.
They can be stored for up to 24 months at about 37 ° C.
Registered and approved by European, American, Chinese, Indonesian, Indian and Canadian health authorities.

ELDONCARD – „Point of care anywhere”.

EldonCard is used in blood banks for testing - especially for new donors, but also for educating new donors. It is the ideal tool to show donors what is happening, at the same time making them understand the importance of becoming a "lifetime" donor.
It is used in the recruitment campaigns of new donors - as a gift, but also for education. ELDON IDENTIFICATION CARD with place for photography The donor is used in particular to recruit new donors and to keep them, giving them a gift.

US blood donation centers have increased Reed cell volume by over 25% using ELDON cards. Blood banks have more chances to get exactly the blood groups they need.
How it works: When they reach the blood collection center or mobile unit, donors are tested with an EldonCard - if the blood group has donors are specifically requested by a Blood Bank, the donor will be sent to "Double Reed Cell Fractionation". This is possible even within the mobile units I use. This procedure will double the amount of reed cells in place. - In this case, EldonCard:

Increase the volume of reed cells.
Improves the economy.
It creates greater flexibility - increased safety for the blood bank.

Many hospitals use EldonCard for the "clinical trial". The use of EldonCard is:

A safe and easy method to perform the clinical trial.
The results can be kept in the patients' diary.
It can be kept in the operating room "on the spot" - it does not require refrigeration.
Result in only 2.5 minutes.

Used by the US Army, US Navy, French, Danish, Norwegian, Swedish, etc. around the world because of the fact that EldonCard it can be used in any conditions, does not require refrigeration or electricity, is stable and precise.

"One Man Kit" designed for field use and for individual soldier safety.
Can be stored in your pocket - easy to carry, easy to use.
The "military kit" designed for campaign hospitals.
A complete kit for use in campaign hospitals, requires only a few drops of drinking water.
Easy to carry - no refrigeration required - easy to store.
Used on military ships, in campaign hospitals.
Used in peacekeeping missions, in areas affected by disasters, such as earthquakes and tsunamis.
It has been tested by the US Military in all conditions - call and we can send you the article from the Medical Journal.

EldonCard and the ELDON EMERGENCY KIT are used by several rescue organizations around the world. The army uses them in peacekeeping missions and in rescue missions, locally and abroad. The KIT can be stored for 24 months without refrigeration - it is easy to carry and transported to all areas of the world. Doctors and laboratory staff believe that it is easy to use, regardless of conditions, and requires only a few drops of drinking water.

ELDON PACKAGE FOR EMERGENCIES AND RESCUE MISSIONS

                               The box contains everything needed to determine the blood group in place.
Oil rigs and cruise lines use them for the safety of guests and crew.

Prevention of erythroblastosis foetalis by injecting antigen D in every woman with negative antigen D, who has given birth to a Rh positive child or who has who did an abortion. Eldon has developed a special card used in hospitals, maternity hospitals, birth clinics and pregnancy cessation.

School kits are the ideal tool for education regarding the human blood system and the different blood groups. An educational tool which offers an impressive perspective and by which one can understand the reasons for becoming a blood donor. It is used in schools and universities.

A practical kit for home use that facilitates home testing. before going on a journey - for the purpose of obtaining a blood identity for one's own safety. Know your own blood group for protection. If you need to know your own blood group regarding your nutrition and health treatments.